Download DNA Computing: 14th International Meeting on DNA Computing, by Ken Komiya, Masayuki Yamamura, John A. Rose (auth.), Ashish PDF

By Ken Komiya, Masayuki Yamamura, John A. Rose (auth.), Ashish Goel, Friedrich C. Simmel, Petr Sosík (eds.)

This booklet constitutes the completely refereed post-conference complaints of the 14th overseas assembly on DNA Computing, DNA 14, held in Prague, Czech Republic, in June 2008.

The 15 revised complete papers offered have been rigorously reviewed and chosen from fifty nine submissions. Their themes comprise theoretical versions of biomolecular computing, demonstrations of biomolecular computing methods, self-assembly platforms, DNA nanostructures and nanomachines, biotechnological and different functions of DNA computing, and different comparable themes.

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6. : From Genes to Machines: DNA Nanomechanical Devices. Trends Biochem. Sci. 30, 119–125 (2005) 7. : DNA-Based Machines. Org. Biomol. Chem. 4, 3392–3401 (2006) 8. : A DNA-Fuelled Molecular Machine Made of DNA. Nature 406, 605–608 (2000) 9. : A Modular DNA Signal Translator for the Controlled Release of a Protein by an Aptamer. Nucleic Acid Res. 34, 1581–1587 (2006) 10. : A Synthetic DNA Walker for Molecular Transport. J. Am. Chem. Soc. 126, 10834–10835 (2004) 11. : Molecular Gears: A Pair of DNA Circles Continuously Rolls against Each Other.

5). On the contrary, the fluorescence became lower after 5 min of UV light irradiation, although the fluorescence was still much higher than that of the completely closed state (compare blue line with green line ---- in Fig. 5). It can be estimated that about 13% of the tweezers were photoregulated to open and close. This lower efficiency of closing the tweezers may be attributed to the insufficient stabilization effect in cis form as we reported recently [18]. When visible light was irradiated for 1 min at this point, the fluorescence increased and the closed tweezers opened again.

The opening and closing are photoregulated to some extent with UV (green lines ----) and visible light (blue lines ⋅⋅⋅⋅) irradiation, respectively. The efficiency for the photoregulation of closing and opening of the tweezers with F12X was estimated by measuring the change of fluorescence with the light irradiation at thermo-stable conditions. As shown in Fig. G. Liang et al. (closed tweezers). On the other hand, when it was irradiated with UV light (330~350 nm) for 5 minutes, the spectra (green lines ----) became close to that of the opening tweezers consisting of only A, B, and C (Fig.

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