Download Diagnostic Nuclear Medicine by Christiaan Schiepers MD, PhD (auth.), A. L. Baert, K. PDF

By Christiaan Schiepers MD, PhD (auth.), A. L. Baert, K. Sartor, Christiaan Schiepers MD, PhD (eds.)

The box of nuclear medication is present process swift growth, and is evolving into diagnostic molecular imaging. in the course of fresh years, dual-modality imaging with PET/CT has won recognition and this can be presently the fastest-growing strategy for oncological imaging purposes. The glucose analogue FDG has held its position in diagnostic oncology, review of myocardial viability and analysis of neuro-degenerative problems. Peptides became much more very important as imaging brokers. The accuracy of hepatobiliary scintigraphy has been more advantageous through cholecystokinin. using ACE inhibitors within the overview of renovascular high blood pressure has develop into the traditional in renography. New instrumentation has resulted in quicker scanners, and computing device improvement to higher photograph processing software program. automated processing is extra universal, and standardization of protocols could be comprehensive simply. the sector of gene imaging has stepped forward, even supposing regimen scientific functions aren't but on hand. the current textual content, supplemented with many precise and informative illustrations, represents an accessory to the normal wisdom of diagnostic nuclear drugs and offers either the coed and the pro with an summary of advancements prior to now decade.

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In recent years there has been a parallel recognition of the usefulness of PET and SPECT in evaluating patients for seizure surgery, but few systematic studies have been performed comparing these two modalities. Most interictal PET studies demonstrate that approximately 70% of patients with severe partial seizures have reduced regional glucose utilization. Interictal hypometabolism is more common in patients with mesial temporal lesions such as hippocampal sclerosis, small tumors and hamartomas, but is less frequently seen in patients without radiographically visible lesions (Engel et al.

Accordingly, PET may provide non-invasive information that helps stratify patients for mesial basal versus lateral neocortical selective temporal lobe surgery. Patients with bilateral hypometabolism have a worse surgical prognosis that those with unilateral hypometabolism (Blum et al. 1998). Interestingly, no quantitative relations have been observed between the presence and magnitude of regional hypometabolism and interictal or ictal electrical parameters (Engel 1988). Accordingly, 18F-FDG metabolic studies appear to be measuring processes different than those reflected by regional electrical activity.

1992; Thomas et al. 1992). Overall, these results demonstrate the high sensitivity in localizing seizure foci comparable to that of 18F-FDG PET (70%), but some studies have shown a lower sensitivity, stimulating the use of ictal SPECT scanning. Due to the longer half-life of SPECT blood flow radiopharmaceuticals, the use of ictal and postictal scanning in patients with epilepsy has been explored in recent years (Magistretti and Uren 1983; Lee et al. 1987, 1988; Devous and Leroy 1989; Rowe et al.

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