Download Current Topics in Developmental Biology, Vol. 34 by Roger A. Pedersen PDF

By Roger A. Pedersen

Quantity 34 keeps the sequence' culture of well timed evaluation and incisive analyses of key examine in developmental biology. not just helpful to researchers on the vanguard of animal and plant improvement, this quantity can also be a pleasant advent to scholars and pros who're enthusiastic about present issues in mobile and molecular mechanisms in improvement.

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Rice, D. A . , and Parker, K. L. (1992). Steroidogenic factor 1, a key regulator of steroidogenic enzyme expression, is the mouse homolog of fushi tarazu factor 1. Mol. Endocrinol. 6, 1249-1258. , and Clevers, H. (1993). Ancestry and diversity of the HMG box superfamily. Nucleic Acids Res. 21, 2493-2501. Lee, C. , and Taketo, T. (1994). YDom sex-reversed mouse gonad. Dev. Biol. 165, 442-452. Lee, F. , and Strauss, J. (1972). The “camptomelic” syndrome. Short life-span 1 . SRY and Mammalian Sex Determination 21 dwarfism with respiratory distress, hypotonia, peculiar facies, and multiple skeletal and cartilaginous deformities.

1994). A. Comparative Overview of Male Pronuclear Development in Vivo Eggs are normally fertilized at one of four maturation stages depending on species (Table I). These are meiotic prophase I (germinal vesicle stage), meiotic metaphase I, meiotic metaphase 11, or after completion of meiosis (pronuclear stage). Oogenesis arrests at these stages, and completion of meiosis or resumption of the cell cycle is normally triggered by the fertilizing sperm. Although the eggs of a given species are typically fertilized at only one stage, some eggs can be fertilized experimentally at stages other than their normal one, this being prevented in nature by avoiding proximity of the gametes (for example, by sequestration in the female) or incapacity of the gamete membranes to fuse.

The exceptionally long sperm enters a micropyle at the anterior end of the egg (Karr, 1991). Meiosis is complete by 10 rnin and approach of the pronuclei occurs 16-17 min after egg laying (Schneider-Minder, 1966). The first nine cycles of nuclear reproduction last 10 rnin with a replication period of 4 rnin (Kriegstein and Hogness, 1974). Cycles 10-13 last about 15 min, so that it takes just over 2 hr for the first 13 divisions producing -6000 nuclei. The syncytium then undergoes cleavage divisions to produce a cellular blastoderm.

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