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By Paul Hyman; Stephen T Abedon; C.A.B. International

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Kuhl et al. cholera outbreaks in the past. The dreaded ‘bad’ Escherichia coli, E. coli O157:H7, too is ‘bad’ particularly because of the prophageencoded Shiga toxin. Lysogen-mediated diseases thus exist as more than just historical oddities. Rather, they can have both real and recent impacts, resulting in substantial morbidity and mortality, even in our otherwise modern world. What do these diseases look like? To orient the reader, in this chapter we provide an overview of various diseases that are associated with virulence factors that are prophage encoded.

2000) Bacterial vaginosis. Annual Review of Medicine 51, 349–356. D. L. (2009) Bacteriophages induced from lysogenic root canal isolates of Enterococcus faecalis. Oral Microbiology and Immunology 24, 278–284. Sulakvelidze, A. and Kutter, E. (2005) Bacteriophage therapy in humans. In: Kutter, E. and Sulakvelidze, A. (eds) Bacteriophages: Biology and Applications. CRC Press, Boca Raton, FL, pp. 381–436. V. V. (1996) Effect of tannic acid on the bacteriophage population of the rumen. 27). V. (1971) The electron-microscopy examination of the microflora of reindeer rumen.

2010) Phage choice, isolation, and preparation for phage therapy. Current Pharmaceutical Biotechnology 11, 2–14. , Manykin, A. and Letarov, A. (2007) The diversity of coliphages and coliforms in horse feces reveals a complex pattern of ecological interactions. Applied and Environmental Microbiology 73, 5975–5981. , Switala-jelen, K. and Miedzybrodzki, R. (2006) Bacteriophage translocation. FEMS Immunology and Medical Microbiology 46, 313–319. S. and Jofre, J. (1995) Bacteroides fragilis and Escherichia coli bacteriophages: excretion by humans and animals.

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