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Kuhl et al. cholera outbreaks in the past. The dreaded ‘bad’ Escherichia coli, E. coli O157:H7, too is ‘bad’ particularly because of the prophageencoded Shiga toxin. Lysogen-mediated diseases thus exist as more than just historical oddities. Rather, they can have both real and recent impacts, resulting in substantial morbidity and mortality, even in our otherwise modern world. What do these diseases look like? To orient the reader, in this chapter we provide an overview of various diseases that are associated with virulence factors that are prophage encoded.
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