Download Autoimmune Bullous Diseases: Approach and Management by Naveed Sami PDF

By Naveed Sami

This ebook makes a speciality of assisting either dermatologists and non-dermatologists method the remedy of every illness in a practical demeanour. each one bankruptcy reports the present literature of remedies for every ailment, score affliction severity, and gives pragmatic guidance in accordance with sickness severity at the utilization of accessible medicines. the present literature doesn't offer powerful instructions. This booklet addresses this deficiency. This booklet might help advisor clinicians in enforcing applicable remedies in accordance with the categorical illness and its severity, and attainable choices in an algorithmic layout. it'll make the administration of those illnesses extra pragmatic according to either the literature and medical event of experts.

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Additional resources for Autoimmune Bullous Diseases: Approach and Management

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2011;29(4):561–4. 018. 27. Zhu YI, Stiller MJ. Dapsone and sulfones in dermatology: overview and update. J Am Acad Dermatol. 2001;45(3):420–34. 114733. 28. Gurcan HM, Ahmed AR. Efficacy of dapsone in the treatment of pemphigus and pemphigoid: analysis of current data. Am J Clin Dermatol. 2009;10(6):383–96. 2165/11310740-000000000-00000. 29. Basset N, Guillot B, Michel B, et al. Dapsone as initial treatment in superficial pemphigus. Report of nine cases. Arch Dermatol. 1987;123(6):783–5. 30. Chatterjee M, Meru S, Vasudevan B, et al.

Generally however oral corticosteroids are required. 5 mg/kg may be enough. Corticosteroid sparing agents such as dapsone (1–2 mg/kg/day), colchicine 34 K. Heelan et al. 5 mg/kg/day depending on TPMT) • Methotrexate(10−20 mg/week) • Intravenous immunoglobulin (IVIg) (2 g/kg monthly) • Rituximab (1 g day 1 and day 15 IV) Fourth line • Complete remission off all treatment or on minimal dose of prednisolone Goal of treatment Fig. 5 mg/kg/day) [especially if photodistributed prominence of lesions] could be added at this point particularly for milder cases to allow a steroid taper.

2009;161:723–31. 45. Smith TJ, Bystryn J. Methotrexate as an adjuvant treatment for pemphigus vulgaris. Arch Dermatol. 1999;135:1275–6. 46. Tran K, Wolverton J, Soter N. Methotrexate in the treatment of pemphigus vulgaris: experience in 23 patients. Br J Dermatol. 2013;169:916–21. 47. Beissert S, Mimouni D, Kanwar AJ, Solomons N, Kalia V, Anhalt GJ. Treating pemphigus vulgaris with prednisone and mycophenolate mofetil: a multicenter, randomized, placebocontrolled trial. J Invest Dermatol. 2010;130:2041–8.

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