By Nigel Arden, Francisco Blanco, C. Cooper, Ali Guermazi, Daichi Hayashi, David Hunter, M. Kassim Javaid, Francois Rannou, Frank Roemer, Jean-Yves Reginster
This Atlas offers an up to date and finished assessment of the old and present views on osteoarthritis, together with the pathophysiology and epidemiology of the disorder. Written through major authors within the box of osteoarthritis, the booklet discusses class, etiology and possibility components for osteoarthritis, the sickness path and determinants of osteoarthritis development, medical good points and analysis in addition to imaging ways to examine joint harm. The Atlas of Osteoarthritis concludes with the most recent therapy updates together with either nonpharmacological and pharmacological remedies, in addition to surgical ideas for sufferers with the ailment. Osteoarthritis is the commonest type of joint affliction inflicting joint discomfort, stiffness, and actual incapacity between adults. it truly is a tremendous factor for either the person and society with its impression on public overall healthiness carrying on with to develop because of the getting older inhabitants, the emerging incidence of weight problems, and the inability of definitive remedies to avoid or halt the development of the disease.
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Additional resources for Atlas of Osteoarthritis
N. 2 Plain radiograph of the normal right knee. This radiograph clearly shows the femur, tibia and fibula. The patella can be seen as faint circular outline overlapping the femur, centred at the widest part of the femur. Image from Abdul-Jabar et al . Femur Patella Tibia Fibula Pathophysiology Osteoarthritis is considered an organ disease that involves the whole joint structure. A gradual loss of articular cartilage in synovial joints is combined with subchondral bone sclerosis, osteophytes at the joint margins and mild, chronic nonspecific synovial inflammation [6,7].
Are osteophytes good or bad? Osteoarthritis Cartilage. 2004;12(suppl A):S53-S54. 26 Sellam J, Berenbaum F. The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis. Nat Rev Rheumatol. 2010;6:625-635. 27 Scanzello CR, Goldring SR. The role of synovitis in osteoarthritis pathogenesis. Bone. 2012;51:249-257. 28 Hill CL, Seo GS, Gale D, Totterman S, Gale ME, Felson DT. Cruciate ligament integrity in osteoarthritis of the knee. Arthritis Rheum. 2005;52:794-799. 29 Hasegawa A, Otsuki S, Pauli C, et al.
The association of bone marrow lesions with pain in knee osteoarthritis. Ann Intern Med. 2001;134:541-549. 63 Xu L, Hayashi D, Roemer FW, Felson DT, Guermazi A. Magnetic resonance imaging of subchondral bone marrow lesions in association with osteoarthritis. Semin Arthritis Rheum. 2012;42:105-118. 54 Chapter 4 Clinical features and diagnosis of osteoarthritis Francisco J. Blanco Clinical criteria for osteoarthritis Clinical criteria will continue to play an important role in the diagnosis of osteoarthritis until a diagnostic method that integrates clinical findings with aetiological, biochemical and histological abnormalities is developed .