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By A. M. Gotto Jr. (auth.), Giancarlo Descovich, Antonio Gaddi, Gianluigi Magri, Sergio Lenzi (eds.)

The advances within the box of atherosclerosis and heart problems proceed at an more and more fast speed and it truly is an laborious activity for these ultimately concerned to take care of with the most recent advancements. The papers awarded on the seventh assembly on Atherosclerosis and heart problems, held in Bologna, as a part of the 9th Centenary of the basis of the collage of Bologna, were gathered jointly the following with the purpose of delivering all of the most recent info for medical professionals and study employees considering this significant department of medication. we're happy so as to thank all those that joined us in celebrating the oldest college on the earth. The medical contributions, of the top point, are legitimate evidence of the culture of replacing reviews and of the continuous up-dating of information within the assorted sectors of lipid metabolism, genetics, physiopathology, pathological anatomy, bio­ chemical and scientific prognosis, vitamin, pharmacological and non-pharmacological ther­ apy. the varied contributions made by means of authors within the box of epidemiology and the prevention of atherosclerosis have been additionally primary because not just examine centres but in addition medical professionals world wide are engaged within the conflict which was once outlined through the WHO, twenty-five years in the past, because the most crucial epidemic of the trendy age.

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Ducimetiere,P. and Richard,J. Epidemiol. 112,388-394. 12. Rose,G. J. (1980) 'Plasma lipids and mortality: a source of error', Lancet 1, 523-525. 13. B. et al. Cancer Inst. 68,915-918. 14. Ass. 248, 2853-2859. 15. A. H. Chronic Dis. 39, 861-870. 16. W. et al. Ass. 257, 943-948. 17. Knekt,P. et al. Epidemiol. 41, 519-530. 18. H. G. Chronic Dis. 33, 311-322. 19. Beaglehole,R. et al. I. 1,285-287. 20. R. Epidemiol. 114,29-40. 21. Epidemiol. 114, 11-20. 7th International Meeting 22. 23. 24. 25. 26.

Finally, the Cholesterol Lowering Atherosclerosis study (CLAS) of 162 patients who had coronary artery bypass surgery showed that lipid modification could also benefit patients with established coronary disease [4]. 5g of niacin reduced LDLcholesterol by 43% and raised HDL by 37% over two years. 5% of the patients taking placebo. Thus, evidence is accumulating that pharmacologic intervention with cholesterol-lowering drugs can reduce the incidence of CHD within a few years. It is also becoming apparent that the greater the magnitude and duration of the decrease in LDLcholesterol and the increase in the HDL-cholesterol, the greater is the reduction of CHD risk.

Med. J. i, 925-929. A. (1978) 'A randomised trial of homeverSUS-hospital management for patients with suspected myocardial infarction' Lancet i, 837-841. R. (1989) 'Models, methods and goals', J. Clin. Epidemiol. 42, 301-308. A. 251, 351-364. A. 248, 1465-77. B. KANNEL Boston University School of Medicine, Section of Preventive Medicine and Epidemiology, 720 Harrison Avenue, Suite 1105, Boston, MA 02118, USA ABSTRACT. flajor contri butors to coronary heart di sease have been identified through epidemiologic research.

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