Download Angiotensin II receptor antagonists : current perspectives by Mancia Giuseppe PDF

By Mancia Giuseppe

On the grounds that angiotensin II is without doubt one of the such a lot effective vasoconstrictors and an enormous stimulus for the secretion of aldosterone from the adrenal gland, the improvement of of angiotensin II inhibitors is a crucial step in regulating blood strain. This type of drug is well-tolerated through pateints and those medicines have the extra virtue over ACE inhibitors in that they're now not linked to cough. simply because so much medicinal drugs will be given as soon as day-by-day and, like ACEIs, they've got an invaluable additive hypotensive influence together with diuretics, they're a welcome healing device within the remedy of high blood pressure. This moment version builds at the good fortune of the 1st and brings to the reader the entire most up-to-date advancements, scientific trial info, and the contributors's own views while treating sufferers with angiotensin II receptors antagonists.

  • offers chapters via recognized members within the fields of either high blood pressure and center failure, specially with reference to pharmacological interventions
  • covers the recent position of AIIR in neuroprotection
  • builds upon the strengths of the 1st edition
  • Show description

    Read Online or Download Angiotensin II receptor antagonists : current perspectives PDF

    Similar cardiovascular books

    100 Questions in Cardiology

    (BMJ Books) UCL Hospitals, London, united kingdom. greater than a hundred questions are replied through top cardiologists. useful consultant to administration of complex occasions. For practitioners and citizens. Softcover.

    Cardiovascular Biomaterials

    Cardiovascular Biomaterials provides present study mate- rial built by way of members from universities und profes- sional laboratories within the UK,USA, Canada, and Germany, each one recognized for his or her skills during this box. The ebook starts with an creation to the paintings of constructing a brand new man made artery, and proceeds throughout the subject matters of the issues and advancements in center valve replacements, vehicle- diac help units, mechanical houses of arteries and arterial grafts, biostability of vascular prostheses, blood compatibility in cardiopulmonary pass, collagenin aerobic- vascular tissues and the pacemaker process.

    Blood Pressure Monitoring in Cardiovascular Medicine and Therapeutics

    During this newly up to date moment variation of Blood strain tracking in Cardiovascular drugs and Therapeutics, William B. White, MD, and a panel of hugely individual clinicians supply a serious assessment of each element of the assessment of hypertension. This contains domestic and ambulatory blood strain tracking, the connection among whole-day blood strain and the heart problems strategy, and the consequences of antihypertensive cures on those blood strain parameters.

    Additional resources for Angiotensin II receptor antagonists : current perspectives

    Example text

    36. Horrobin DF. Modern biomedical research: an internally self-consistent universe with little contact with medical reality? Nat Rev Drug Discov 2003; 2:151–4. 37. Weinmann AS. Novel ChIP-based strategies to uncover transcription factor target genes in the immune system. Nat Rev Immunol 2004; 4:381–6. 38. Akishita M, Horiuchi M, Yamada H et al. Inflammation influences vascular remodeling through AT2 receptor expression and signaling. Physiol Genomics 2000; 2:13–20. 556 44 7/3/06 4:06 pm Page 44 Stimulation of AT2 receptors 39.

    Angiotensin II receptor blockers and cardiovascular outcomes: what does the future hold? J Renin Eng Ald Syst 2003; 4:62–73. 556 7/3/06 4:06 pm Page 31 Stimulation of AT2 receptors: role in the effect of angiotensin II receptor antagonists 3 Heiko Funke-Kaiser, Ulrike Muscha Steckelings, and Thomas Unger Introduction This chapter will focus on the hypothesis that angiotensin AT1 receptor blockers (ARBs) act not only by blocking the deleterious effects of angiotensin II type 1 receptor (AT1R) activation but also by indirectly activating the angiotensin II type 2 receptor (AT2R).

    20. Zhang J. Pharmacological effects of angiotensin II and non-peptidergic receptor antagonists. PhD Thesis (ISBN 90-9008377-4), University of Amsterdam, 1995; 145. 21. Zhang J, Pfaffendorf M, Zhang JS, van Zwieten PA. A non-competitive type of angiotensin IIreceptor antagonism by losartan in renal artery preparations. Eur J Pharmacol 1994; 252:337–40. 22. Baan H, Chang PC, Vermeij P, Pfaffendorf M, van Zwieten PA. Effects of losartan on vasoconstrictor responses to angiotensin II in the human forearm vascular bed of healthy volunteers.

    Download PDF sample

    Rated 4.00 of 5 – based on 20 votes